Glucosamine and chondroitin supplements do not work

And most of that has to do with the
supplements glucosamine and chondroiton
which you see sold or marketed together.
Which to be honest have mostly negative
results in very large-scale studies that
have been done.
To test whether or not they help with,
joint health.
One of the most well-known studies, was
the GAIT trial; glucosamine, chondroitin,
and arthritis intervention trial of 2006.
Which, bottom line, found no clear
benefit, for most people taking these
products.
In the, in the majority of these studies,
any of the benefit that was realized, was
attributable, to the placebo effect.
In 2009, there was a random Randomized
study that showed glucosamine and
chondroitin were no more effective than
the placebo was to slow cartilage damage
from osteoarthritis.
And again in 2010 there was a different
study done by a group of Norwegian
researchers who tested glucosamine for
chronic low back pain and degenerative
lumbar osteoarthritis and found that
there was no significant difference
between glucosamine and placebo.
So at the end of the day glucosamine is
not or hasn't been proven to be harmful,
but it certainly has been proven not to
help improve joint pain.